Structural investigation of drug delivery systems consisting of biohybrids

TITLE OF THE PROJECT: Structural investigation of drug delivery systems consisting of biohybrids
based on DNA, biomimetic membranes, “green” nanometals and therapeutic agents
THEME: 04-4-1141-2020/2022
YEAR: 2020
LABORATORY IN JINR: Frank Laboratory of Neutron Physics (FLNP)
PARTNERS IN ROMANIA: Faculty of Physics, University of Bucharest (FFUB)
RESPONSIBLE PERSONS: Lect. dr. Marcela-Elisabeta Barbinta-Patrascu (FFUB), Senior Researcher
dr. Yulia Gorshkova (FLNP)
OBJECTIVES:
- the eco-design and complex characterization of innovative biohybrids with multifunctionality
ESTIMATED RESULTS:
The main results expected from this investigation are:
• “green” preparation of biohybrids based on DNA, liposomes and metallic nanoparticles
• spectral, structural and morphological characterization
• evaluation of biological performances of obtained materials (antioxidant capacity,
antimicrobial action, haemolytic activity, antiproliferative activity)