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  Aix-Marseille Université, PI: Christian G Benar, PhD

• Expertise: The Dynamap team (lead CG Bénar) of the "Institut de Neuroscience des Systèmes" (INS,
  Inserm & AMU) has extensive experience in signal processing for multimodal brain mapping in basic
  neuroscience and epilepsy. The team performed the first EEG-MEG-SEEG trimodal recordings, in
  collaboration with F.-Xavier Alario from the "Laboratoire de Psychologie Cognitive" (CNRS & AMU).
  Daniele Schon is the head of Dynamics of Cognitive processes at INS; Agnès Trébuchon is a
  neurologist (MD-PhD and Professor) within the INS and the clinical neurophysiology department of
  the Timone hospital. All are experts in SEEG for cognitive protocols. V Jirsa is the head of the INS and
  an expert in computational modelling and brain dynamics. F Bartolomei is the head of the clinical
  neurophysiology unit. R Carron is the neurosurgeon performing implantation of SEEG electrodes. JM
  Badier is the chief engineer of the MEG centre, who in charge of conducting MEG-EEG-SEEG
  recordings.

  Bucharest University, Physics Department, PI: Andrei Barborica PhD, Co-PI: Ioana Mîndruta MD PhD

• A multidisciplinary clinical and research group performing SEEG has been established in
  2011, comprising physicists/biomedical engineers from Physics Department (A Barborica, C Donos),
  epileptologists from University Hospital (I Mindruta) and neurosurgeons from Bagdasar-Arseni
  Emergency Hospital (J Ciurea). The group has extensive expertise in intracranial signal analysis,
  cortico-cortical evoked potentials and effective brain connectivity. The Epilepsy Unit at the Bucharest
  University Emergency Hospital is the only referral center that performs iEEG in Romania. The
  collaboration between the three departments, has allowed the exploration since mid-2012 of ~65
  patients, at a rate of about 15 patients per year. The unit currently hosts 2 beds with long-term
  video-EEG/video-iEEG recordings operating 24/7 with a staff of EEG technicians. Research-grade
  high-resolution (4096 Hz sampling rate) SEEG recordings are being performed routinely, with the unit
  upgrading to 128 channels this year. State-of the art electrical stimulation using standard (1Hz &50
  Hz) and innovative protocols are implemented using a clinical waveform stimulator. These
  capabilities have allowed the development of a strong clinical program, also providing original
  datasets allowing the analysis of epileptogenicity biomarkers and effective brain connectivity.

Hôpitaux Universitaires de Genève, PI: Serge Vulliemoz, MD, PhD

• S. Vulliemoz has a dual training of physicist and epileptologist with long standing expertise
  in scalp and invasive EEG. He is one of the senior clinicians in the EEG and epilepsy unit, the largest
  Swiss centre for presurgical evaluations in epilepsy evaluating both adults and children.
  His research activity focuses on the investigation of functional networks in patients with epilepsy
  using high density EEG and simultaneous EEG and fMRI recording. Recent research includes new
  methodological development and clinical application of electric source imaging and functional
  connectivity analysis between brain sources using non-invasive EEG recordings. This allows to track
  connectivity changes during transient epileptic activity with very high temporal resolution. It also
  allows to detect functional connectivity changes in the absence of visible epileptic activity.
  Multimodal recordings using invasive EEG include pioneering work in simultaneous intracranial EEG
  and fMRI as well as simultaneous intracranial EEG and high-density scalp EEG.